Transdermal drug delivery system thesis

Also provided within the reservoir 14 adjacent to and operatively associated with the face 14b, and visible through the patch backing, is a microencapsulated color indicator designated generally by the reference numeral 28. This indicator may be designed to change color in response to the presence of water, electrolyte or other secretion, and may be manufactured from inorganic salts that will change color with hydration (for example, anyhdrous copper sulfate or cobalt chloride). Alternatively, colorful dyes (like amaranth or mercurochrome) can be microencapsulted to effect a color change when released. The utility of such an indicator is that it exploits the common mechanism for activating both the indicator's color change and the process for drug release, namely, the ease with which water, electrolyte or other secretion penetrates the coating material of the microcapsules.

Transdermal drug delivery system thesis

transdermal drug delivery system thesis

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